Indole-3-methanol

Inkcazelo emfutshane:

I-Indole-3-methanol isityalo esitsha se-metabolite sesibini esiveliswa kwimifuno ye-cruciferous, enokuthi ikhutshwe kwimifuno ye-cruciferous (efana ne-broccoli, i-radish kunye ne-cauliflower).Indole-3-carbinol yi-tumor chemopreventive substance.I-Indole-3-carbinol inokuthintela ukwenzeka kunye nokuphuhliswa kweentlobo ezahlukeneyo ze-tumor.I-Indole-3-methanol yayisetyenziselwa ukufaka i-poly lactic acid co glycolic acid (PLGA) ukufunda umphumo wayo we-anticancer kwiiseli ze-adenocarcinoma epithelial (MCF7), iiseli ze-colon adenocarcinoma epithelial (Caco2) kunye neeseli ze-prostate epithelial cells (PC3) kwi-vitro.Ikwasetyenziswa njenge-inducer ye-cytochrome P4501A (CYP1A).

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo

I-Indole-3-methanol (I3C) yenza i-aromatic hydrocarbon receptor (AHR) kwaye ibangele ukubanjwa kwe-cell cycle ye-G1 kunye ne-apoptosis.Ngoko ke, yinto enokubakho ye-anticancer.Ukongezelela, ibangela i-estradiol metabolism ngokuvuselela i-cytochrome P450 enzyme.Ke ngoko, i-I3C ithathwa njengeyeza elisebenzayo lechemotherapy kwiindidi ezahlukeneyo zomhlaza, kubandakanya umhlaza webele, umhlaza weprotate, umhlaza wekoloni kunye neleukemia.I-Indole-3-methanol inokuphembelela kuphela i-apoptosis yeeseli zomhlaza, ekhuselekileyo kwaye engeyiyo i-cytotoxic kwiiseli ezingenayo ithumba.Ngenxa yokusebenza kwayo okuphezulu, i-non-toxic and natural anti-tumor properties, i-indole-3-methanol ingasetyenziswa njengomnye wabaviwa bokuthintela umhlaza kunye neziyobisi zonyango.

Ulwazi lweMveliso

Inombolo yeCas: 700-06-1

Ucoceko:≥98%

Ifomula:C9H9NO

Ifomula Wt.:147.17

Igama leMchiza: INDOLE-3-CARBINOL

Isithethantonye: Indole-3-carbinol, 99.5%;Indole-3-carbinol98%;(1H-Indol-3-yl)-methano;I-Indol-3-yl-methanol;I-3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Indawo yokunyibilika: 96-99 °C

Indawo yokuBilisa:267.28°C

Imbonakalo:Kumhlophe-kumhlophe ukuya kumgubo wekristale otyheli-orenji okanye iiflakes