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Iimveliso

I-2-Phenylacetophenone

Inkcazelo emfutshane:

I-Diacetophenones luhlobo lwamayeza abalulekileyo, incasa kunye nevumba eliphakathi.Kwiminyaka yakutshanje, zisetyenziswa kakhulu kwi-synthesis ye-antipyretic, analgesic, anti-inflammatory and estrogen drug (Estrogen Pharmaceutical Agents).I-Estrogen ubukhulu becala idlala indima yolawulo lwe-endocrine kwinkqubo yokuzala yee-vertebrates, kodwa nayo inefuthe elibaluleke kakhulu kumalungu amaninzi enkqubo yokuzala, njengamathambo, isibindi, inkqubo ye-cardiovascular system, inkqubo ye-nervous central njalo njalo.Izifo ezinxulumene ne-estrogen ikakhulu ziquka: umhlaza webele, umhlaza wesibeleko, umhlaza wekoloni, isifo sika-Alzheimer, umkhuhlane obomvu kunye nezifo ezithile zabasetyhini abayeka ukuya exesheni (ezifana ne-osteoporosis).Uphononongo lwakutsha nje lubonise ukuba iindidi ezininzi zeekhompawundi ze-heterocyclic ezenziwe kwi-benzophenones ziyasebenza ngokuchasene neeseli zomhlaza.Ezi khompawundi heterocyclic ikakhulu: Isoflavonoid (Isoflavonoid), azole ring (Azole), imidazole ring (Imi-dazole), thiazole iringi (Thiazole), isoxazole iringi (Isoxa-zole), pyrazole Imisesane (Pyrazole), apho pyrazole kugqibelele.


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ulwazi lweMveliso

INOMBOLO YECAS: 451-40-1
Ubunyulu: ≥99%
Ifomula: C14H12O
Ifomula Wt: 196.24
Isithethantonye: 1,2-Diphenylethan-1-enye;Benzylphenylketone, Deoxybenzoin;Phenylmethylphenylketone;I-Deoxybenzoin98%;ValdecoxibDeoChemicalbookxyBenzoin(BenzylPhenylKetone);ValdecoxibDeoxyBenzoin(BenzylPhenylKetoneOkanye; Deoxybenzoin,97%; DIPHENYLETHYLKETONE
Indawo yokunyibilika: 54-55°C
Indawo yokuBilisa: 320°C
Indawo edanyazayo: >230°F
Ukunyibilika: i-methanol: 0.1g/mL, icacile
Imbonakalo: Umgubo weCrystalline

Ukuthumela ngenqanawa kunye noGcino

Ubushushu bokugcina: 2-8°C

Iimpawu zeMichiza Iikristale ezimthubi kancinane.Indawo yokunyibilika 53-60℃.Inyibilika etywaleni, iketone, iether, inyibilika kancinane emanzini ashushu.Indawo yokubilisa 320℃.Sebenzisa i-Intermediate ye-triphenylamine.Ukuveliswa kwe-MethodPhenylacetic acid ithathwa kunye ne-phosphorus trichloride ukwenza i-phenylacetyl chloride, kwaye emva koko isabelane ne-benzene xa kukho i-anhydrous aluminium trichloride.Imveliso yokusabela ikhutshwa ngumphunga iphume kwibenzene egqithisileyo phantsi koxinzelelo olucuthiweyo, iqhubeke idistil phantsi koxinzelelo olucuthiweyo kwaye iqokelele iqhezu kwi-160℃ (0.67kPa), eyi-diphenylacetophenone.I-Diphenylacetophenone inokutsha kwaye inetyhefu, kunqande ukudibana nolusu kunye namehlo, kunqande ukuphefumla uthuli, ukungabikho kwedatha yetyhefu ethile, ubuthi bayo bunokubhekiswa kwi-acetophenone.
Ubuthi kunye nempembelelo yokusingqongileyo: i-diphenylacetophenone yikhemikhali enetyhefu, ukuphepha ukudibanisa nolusu kunye namehlo, ukuphepha ukuphefumla uthuli.Iigundane nge-intravenous LD50: 320 mg / kg, akukho datha yetyhefu ethile ngaphandle kwedosi ebulalayo, ubuthi bayo bunokubhekiswa kwi-acetophenone.
Ukupakishwa, ukugcinwa kunye nokuthutha: Ipakishwe kwi-20kg okanye i-50kg ye-cardboard drums efakwe ifilimu yeplastiki kwaye igcinwe kwindawo epholileyo, eyomileyo, nengena umoya, kude nezinto ezingahambelaniyo ezifana ne-oxidizers eqinile.Ukuthutha ngokwemichiza eyityhefu enokutsha.


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