M-chlorodiphenylamine

Ifomula yemolekyuli: C12H10ClN

Ubunzima bemolekyuli: 203.67

Inombolo ye-EINECS: 202-922-0

Iindidi ezinxulumeneyo:I-Organic Chemistry;Aromatics

Ifayile ye-Mol: 101-17-7.mol

Indawo yokunyibilika: 112°C (Solv:methanol(67-56-1))

Indawo yokubila: 340°C

Ubuninzi: 1,21g/cm3

Isalathiso se-refractive: 1.6513 (uqikelelo)

Iimeko zokugcina: 2-8°C

Ukunyibilika: I-Chloroform (Kancinci), i-MethChemicalbookanol (Kancinci)

I-Acidity coefficient: (pKa)-0.20±0.30(Kuqikelelwe)

Ifomu: Oyile
Umbala: Mthubi Wamthubi ukuya kumthubi

Idatha ye-CAS: 101-17-7 (I-CASDataBaseReference)

Umsebenzi we-Biological: I-3-Chlorodiphenylamine i-high-affinity cardiac Ca2 + sensitizer (Ca2 + sensitizer).I-3-Chlorodiphenylamine isekelwe kwisakhiwo se-diphenylamine kwaye inokubophelela kwi-N-terminal domain ye-cardiac troponin C (cTnC) (Kd = 6µM).I-3-Chlorodiphenylamine, ngenxa yobungakanani bayo bemolekyuli encinci, inokusebenza njengesiqalo esihle kakhulu sokuphuhliswa kwe-Ca2 + iikhompawundi ezinamandla zokuvavanya ukusilela kwentliziyo ye-systolic.

I-Kd ekujoliswe kuyo: 6µM(N-domainofcardiactroponinC(cTnC))Kd:10µM(cNTnC–cSpchimera)

Iimpawu zeMichiza: Ulwelo.Indawo yokubilisa: 335-336 ℃ (96.3kPa), ukuxinana kwe-1.200, i-refractive index 1.6513.Inyibilika kwi-ethanol, benzene, iacetic acid kunye ne-ether.

Usebenzisa: m-chlorodiphenylamine yi-organic intermediate of diphenylamine, esetyenziselwa ukuvelisa ichiza chlorpromazine.
iindlela zokuvelisa : nge-condensation ye-o-chlorobenzoic acid kunye ne-m-chloroaniline, kwaye emva koko i-decarboxylated nge-iron powder.

Ikhowudi yecandelo lengozi: 20/21/22

Imiyalelo yoKhuseleko: 28-36/37