Iimveliso
Thymidine
Ifomula yoLwakhiwo
Ngokwasemzimbeni
Imbonakalo:Umgubo weCrystalline omhlophe
Umbala:mhlophe Ukuya Phantse Mhlophe
Ubuninzi: 1.3129 (Uqikelelo olurhabaxa)
Indawo yokunyibilika:186-188 °c(lit.)
Indawo yokuBilisa:385.05°c (Uqikelelo olurhabaxa)
I-refractivity: 33 °(c=1, 1mol/l uNaho)
Ukujikeleziswa okuthe ngqo:18.6 º(c=3, H2o)
Imeko yoGcino:2-8°c
I-Acidity Factor(pka):pk1:9.79;pk2:12.85 (25°c)
I-Spinability: α]20 / d +19±1 °, C = 1% Kwi-H2o
Ukunyibilika emanzini: ukunyibilika
Uzinzo: uzinzile.Ayihambelani ne-Agents eqinile ye-Oxidizing
Idatha yoKhuseleko
Udidi lwengozi:Ayiyompahla eyingozi
Inombolo yothutho lwempahla eyingozi:
Udidi lokuPakisha:
Isicelo
1.Isetyenziswa njengendawo ephakathi yoxubo lokwenziwa kwamachiza alwa nentsholongwane kaGawulayo kunye nentsholongwane kaGawulayo.
2.Njengomphakathi weZivdodine
Ukusetyenziswa:
I-Thymidine yi-deoxyribonucleoside equlethe isiseko se-thymine.I-Thymidine yi-nucleoside eyenziwe ngokudibanisa i-thymidine ne-D-ribose nge-b-glycosidic bond.I-Thymidine isetyenziselwa ukwenza amachiza okulwa noGawulayo (umzekelo, i-zidofuridine, i-stavudine) kunye nokudibanisa amachiza okulwa nentsholongwane.Isenokusetyenziswa njengendawo ephakathi yamayeza kwaye ithunyelwe kumazwe angaphandle ngokuthe ngqo.
I-Bioactivity:
I-Thymidine(i-Deoxythymidine, i-2'-Deoxythymidine, i-5-Methyldeoxyuridine, i-DThChemicalbookyd, i-NSC21548) yi-nucleoside ye-pyrimidine equka i-thymine, isiseko se-pyrimidine esidityaniswe kwi-sugar deoxyribose.Njengenxalenye ye-DNA, i-thymine nucleosides idibanisa ne-adenine kwi-DNA double helix.
