I-Retinoic Acid

Isicelo

I-Retinoic acid (i-tretinoin) iphuma kwi-vitamin A.Ibonise amandla okuguqula i-collagen synthesis, ukwandisa amanqanaba e-dermal hyaluronic acid, kunye nokuvuselela ukukhula kwe-fibroblast kunye ne-matrix engaphandle.Isetyenziselwa ukuphazamiseka kwe-keratinization kunye nokunyanga i-acne.
I-Vitamin A, kunye ne-molecular formula C20H28O2, yimveliso ye-metabolic ephakathi ye-vitamin A emzimbeni, ikakhulukazi echaphazela ukukhula kwamathambo kunye nokukhuthaza imiphumo ye-metabolic ye-epithelial cell proliferation, umahluko kunye ne-keratinolysis.Isetyenziselwa unyango lwe-acne vulgaris, i-psoriasis, ichthyosis, i-lichen planus, iinwele ezibomvu ze-furunculosis, i-follicular keratosis, i-squamous cell carcinoma kunye ne-melanoma.
Udidi: Izinto ezingaqhelekanga zokulwa ne-keratinization yesikhumba, ii-ejenti zokwahlula iiseli
Iimeko zokugcina: ukukhanya-ukukhanya kunye nokutywinwa
I-Retinoic acid ayinayo impembelelo kumsebenzi we-tyrosinase kunye nokubunjwa kwe-melanin ye-melanocytes yabantu eqhelekileyo.Xa ulusu lufumana ukuguga komzimba okanye lonakaliswe ngamachiza, imitha ye-UV okanye i-trauma, i-retinoic acid ilungisa okanye ithintele ukungahambi kakuhle kwi-biochemical composition kunye ne-morphological structure ye-dermal connective tissue ebangelwa yimiba eyingozi.I-asidi ye-retinoic ayinayo impembelelo kwi-collagen yesikhumba eqhelekileyo.Ukongezelela, i-retinoic acid inomsebenzi wokuthintela kwi-leukocyte chemotaxis, ngaloo ndlela isebenza njenge-agent anti-inflammatory.I-asidi ye-Retinoic ayinayo impembelelo ngokuthe ngqo kwiingqungquthela ze-sebaceous kunye nemfihlo yazo.