ibhanile12

Iimveliso

I-Orlistat

Inkcazelo emfutshane:

Igama lemveliso: Orlistat
Inombolo yeCAS: 96829-58-2
Inombolo yokungena ye-EINECS: 639-755-1
Ifomula yemolekyuli: C29H53NO5
Ubunzima bemolekyuli: 495.73


Iinkcukacha zeMveliso

Iithegi zeMveliso

Ifomula yoLwakhiwo

13

Iipropati Zomzimba
Ukubonakala: umgubo omhlophe wekristale
Ubuninzi: 0.976±0.06
Indawo yokunyibilika:<50°C<br /> Indawo yokubila: 615.9±30.0°C

Idatha yoKhuseleko
Udidi lwengozi: Impahla ngokubanzi

Isicelo
Udibaniso lokutya okunekhalori ephantsi lufanelekile kunyango lwexesha elide lwabantu abatyebe ngokugqithiseleyo nabatyebe ngokugqithiseleyo, kuquka abo baye baphuhlisa izinto ezinobungozi ezinxulumene nokutyeba.Inefuthe lokulawula ubunzima bexesha elide (ukulahleka kwesisindo, ukugcinwa kwesisindo kunye nokuthintela ukuphindaphinda).Ukuthatha ichiza kunokunciphisa izinga lezehlo zokutyeba ezinxulumene nemiba yomngcipheko kunye nezinye izifo ezinxulumene nokutyeba, kubandakanya i-hypercholesterolemia kunye nohlobo lwesi-2 seswekile.

I-Orlistat i-arhente engeyiyo ye-CNS-esebenza kunyango lokukhuluphala.Isebenza kuphela kumzila wesisu, ukuthintela i-hydrolysis ye-triacylglycerols kwi-fatty acids yamahhala kunye ne-monoacylglycerides ngokuvimbela i-lipase kwi-gastrointestinal tract, ukunciphisa ukufunxa kwamafutha okutya (i-triacylglycerols) nge-intestinal mucosa, kunye nokukhuthaza ukutshatyalaliswa komzimba. .I-Lipase yi-enzyme eyimfuneko yokubola kwamafutha kwi-gastrointestinal tract.Le mveliso inokudibanisa kunye neentsalela ze-serine ze-gastric kunye ne-pancreatic lipase ukuze ingasebenzi i-lipase, ukwenzela ukuba ingakwazi ukubola amanqatha ekudleni kwi-fatty acids yamahhala kwaye inqanda ukusetyenziswa kunye nokufunxa kwamafutha.
Izilumkiso: 1. Izigulane ezityebileyo kunye nohlobo lwe-2 yesifo sikashukela zinciphisa ubunzima emva kokunyanga kunye nale mveliso, zihlala zihamba kunye nokulawulwa kwe-glycemic ephuculweyo, kwaye kufuneka kulungiswe iziyobisi ze-hypoglycemic ukuze zigweme i-hypoglycemia.
2. Abasetyhini abakhulelweyo nabancancisayo, abantwana abangaphantsi kweminyaka eyi-18 ubudala kunye nabaselula abazange bafundelwe ukhuseleko kunye nokusebenza kakuhle, musa ukusebenzisa.


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