ibhanile12

Iimveliso

Citrulline

Inkcazelo emfutshane:

I-Citrulline i-α- Amino acid, kunye ne-chemical formula ye-C6H13N3O3, yimveliso eyenziwe kwi-ornithine kunye ne-amino formyl phosphate kumjikelezo we-urea, okanye ukusuka kwi-arginine ekhutshwe yi-nitric oxide synthase (NOS) ukuya kwiNombolo.

Izigulane ezine-rheumatoid arthritis (malunga ne-80%) zihlakulela impendulo yokuzivikela kwiiprotheni ezine-citrulline.Nangona unobangela wale ndlela yokusabela ungaziwa, ukufunyaniswa kwezilwa-buhlungu kunokunceda ekufunyanisweni kolu hlobo lwesifo.

 


Iinkcukacha zeMveliso

Iithegi zeMveliso

Inkcazo

Xa i-citrulline iseyi-amino acid, kuba ayifakwanga kwi-DNA, ayiyi kufakwa kwiiprotheni kwi-protein biosynthesis, kodwa ezinye iiprotheni zisene-citrulline.Ezi citrulline ziveliswa yi-peptide arginine iminase (PAD), eguqula i-arginine kwi-citrulline ngexesha le-melonization.Ngokuqhelekileyo, iiprotheni eziqulethe i-citrulline ziquka iprotheni esisiseko ye-myelin (MBP), i-polykeratin microfilament kunye nezinye i-histones.Ngokomzekelo, i-cellulose kunye ne-vimentin inokuhlanjululwa ngokufa kweeseli kunye nokuvutha kwezicubu.

Ulwazi lweMveliso

Inombolo yeCas: 372-75-8

Ubunyulu:≥98.5%

Ifomula yomgaqo: C6H13N3O3

Ifomula Wt.Yona: 175.19

4

Igama leKhemikhali: Urea aminovaleric acid:

Igama le-IUPAC: Urea aminovaleric acid

Indawo yokunyibilika: 222 ℃

Ukunyibilika:Inyibilika emanzini

Imbonakalo :Ikristale emhlophe

Ukuthumela ngenqanawa kunye noGcino

Gcina iTemp:2-8ºC

Ngenqanawa Temp
I-Ambient

Iimbekiselo

1.Wan Xueshan, liuwenge, yanzhihong, etc Utshintsho imixholo lycopene, citrulline, VC kunye nezinye izinto ezisebenzayo ngexesha lophuhliso iziqhamo ivatala.VIP, 2011

2.Liu Juan, uLu Xinxin, uMeng Hui Inkqubela phambili yoPhando kwimiphumo ye-pharmacological kunye neendlela zokuvelisa i-citrulline.CNKI;Wanfang, 2011

3.Huang Jing, Lin Hua, Wang Yongxin, Yao di Ukubaluleka kokufunyanwa okudibeneyo kwe-anti cyclic citrullinated peptide antibody, i-anti keratin antibody, i-anti perinuclear factor antibody kunye ne-rheumatoid factor ekuxilongweni kwe-rheumatoid arthritis endala.CNKI, 2010


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