Adenine

Isicelo
I-purine nucleobase kunye nenxalenye yeDNA.Isasazeke kuyo yonke izicubu zezilwanyana kunye nezityalo ezidityaniswe ne-niacinamide, i-d-ribose, kunye ne-phosphoric acid;i-nucleic acid kunye ne-coenzymes, njenge-codehydrase I kunye ne-II, i-adenylic acid, i-coa laninedehydrase.Isetyenziselwa ukuzimisela kwe-microbial ye-niacin;kuphando ngemfuzo, izifo zentsholongwane, kunye nomhlaza.ukutyabeka kwe-enteric kunye ne-antiseptic yendawo

I-Adenine, eyaziwa ngokuba yi-6-aminopurine, yenye yeenucleobases ezine ezenza i-DNA kunye ne-RNA i-molecule, kunye ne-chemical formula C5H5N5.Ibandakanyeka ekubunjweni kwezinto ezininzi ezibalulekileyo ezifana ne-ATP kunye ne-NADP kwiindlela ze-metabolic emzimbeni.
I-Adenine iyinxalenye ye-nucleic acids kunye ne-coenzymes, ebandakanyekayo kwi-synthesis ye-DNA kunye ne-RNA emzimbeni, kwaye ibalulekile ekugcinweni kwemisebenzi ye-metabolic yezinto eziphilayo.Indima yayo kukukhuthaza ukwanda kwe-leukocytes kwimeko yokusilela.
Ukudibanisa
I-Adenine anabolism ibandakanya zombini i-ab initio kunye neendlela zokulungisa zokwenziwa.I-ab initio synthesis pathway ngokuyinhloko kwisibindi kwaye isekelwe kwi-ribose phosphate, i-aspartate, i-glycine, i-glutamine, kunye neeyunithi zekhabhoni enye.I-nucleotides ye-Purine idityaniswa ngokuqhubekayo kwisiseko se-phosphoribose molekyuli, kungekhona ngokuqala ukudibanisa iziseko ze-purine zodwa kwaye emva koko zidibanise ne-phosphoribose.I-synthesis yokulungisa i-nucleotides ye-purine ikakhulu ngenxa yokungabikho kweenkqubo ze-enzymatic ze-ab initio synthesis ye-purine nucleotides kwizicubu ezithile kunye namalungu omzimba, njengengqondo kunye nomnkantsha wethambo, ukwenzela ukuba kuphela le ndlela inokwenziwa, kwaye oku. indlela igcina amandla kunye nokunye ukusetyenziswa kwe-amino acid ngexesha le-ab initio synthesis.